Regulation of NFKB signalling: Neurotensin suppresses the expression of TNFAIP3, the negative regulator of NFKB, via down regulation of its target gene, 27/February/2015, 23.22

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Regulation of NFKB signalling: Neurotensin  suppresses the expression of TNFAIP3, the negative regulator of NFKB, via down regulation of its target gene, 27/February/2015, 23.22, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance:  This study suggests, for the first time, that Neurotensin, by decreasing the expression of its target gene, it may suppress the expression […]

MiRNA-based anti-tumor immunity enhancement therapy: MiRNA-128-2 promotes anti-tumor immunity via down regulation of its target gene, 27/February/2015, 23.02

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, MiRNA-based anti-tumor immunity enhancement therapy: MiRNA-128-2 promotes anti-tumor immunity via down regulation of its target gene, 27/February/2015, 23.02, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance:  This study suggests, for the first time, that MiRNA-128-2, by inducing the expression of its target gene, it may promote anti-tumor immunity.  Thereby, it may inhibit tumor progression. […]

MiRNA-based therapy for Melonama: MiRNA-203 increases the expression of ADAR1 and inhibits melanoma progression via down regulation of its target gene, 27/February/2015, 09.10 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, MiRNA-based therapy for Melonama:  MiRNA-203 increases the expression of ADAR1 and inhibits melanoma progression via down regulation of its target gene, 27/February/2015, 09.10 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Significance:  This study suggests, for the first time, that MiRNA-203, by inducing the expression of its target gene, it may increase the expression […]

Molecular therapy for cancer: Tumor suppressor p53 increases the expression of oncogenic suppressor PTX3 and inhibits complement-dependent inflammation in cancer via down regulation of its target gene, 27/February/2015, 9.07 am

A recent study from the Humanitas Clinical and Research Center, Rozzano (Milan) 20089, Italy shows that “PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer.” This study was published in the 12 February  2015 issue of Cell [I.F:33] by Drs. Alberto Mantovani , Eduardo Bonavita and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for cancer: […]

Natural product-based therapy for Emphysema: Fisetin, a flavonoid enriched in strawberries, Mangoes and Cucumber, inhibits inflammation and protects against Emphysema via up regulation of its target gene, 27/February/2016, 9.01 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Natural product-based therapy for Emphysema: Fisetin, a flavonoid enriched in strawberries, Mangoes and Cucumber, inhibits inflammation and  protects against Emphysema via up regulation of its target gene, 27/February/2016, 9.03 am, http://genomediscovery.org Significance: This study suggests that Fisetin, by increasing the expression of its target gene, may protect against Emphysema. Thus, this study suggests that pharmacological formulations encompassing “Fisetin or […]

Insights into Weight loss therapy: CDX2 inhibits hepatic steatosis and promotes weight loss via down regulation of Nocturnin, 27/February/2015, 8.56 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Insights into Weight loss therapy: CDX2 inhibits hepatic steatosis and promotes weight loss via down regulation of Nocturnin, 27/February/2015, 8.56 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org Web: http://genomediscovery.org Courtesy: When you cite drop us a line at info@genomediscovery.org Significance:  CDX2, by increasing the expression of its target gene, it may decrease the expression of […]