February

February 14, 2015

Small molecule-based Regenerative Stem cell therapy for Myocardial Infarction: Paracetamol (4-Hydroxyacetanilide) improves ageing- and stress-associated decline in cardiac function via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 14/February/2015, 23.40

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On […]
February 14, 2015

MiRNA-based therapy for Pulmonary Hypertension (PAH): MiRNA-99 inhibits pulmonary hypertension via induction of PDLIM5, 14/February/2015, 23.22

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests, for the first time, that MiRNA-99 may increase the expression of PDLIM5. Thereby, […]
February 14, 2015

Natural product-based therapy for cancer: Tumor suppressor p53 homologues p73 and p63 suppress the expression of oncoprotein Mcl-1 and increase the expression of proapoptotic protein BIM via down regulation of their target genes, 14/February/2015, 23.17

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Natural product-based therapy for cancer: Tumor suppressor p53 homologues p73 and p63 suppress the expression of […]
February 14, 2015

Molecular therapy for Cancer: Tumor suppressor p53 suppresses the expression of 6-phosphofructo-2-kinase/fructose‑2,6-bisphosphatase-3 (PFKFB3) and inhibits proliferation, migration, and invasion of cancer cells via up regulation of its target gene, 14/February/2015, 13.14

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Molecular therapy for Cancer: Tumor suppressor p53 suppresses the expression of 6-phosphofructo-2-kinase/fructose‑2,6-bisphosphatase-3 (PFKFB3) and inhibits proliferation, […]