February

February 11, 2015

Molecular therapy for T2DM: β-catenin promotes gluconeogenesis and hyperglycemia via up regulation of Cyclin D1, 11/February/2014, 23.19

A study from the Department of Cancer Biology, Dana-Farber Cancer Institute;  Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA; and others shows that “Cyclin D1–Cdk4 controls glucose metabolism independently of […]
February 11, 2015

AntagomiR-based therapy for pulmonary arterial hypertension: MIRNA-7 increases pulmonary arterial hypertension via down regulation of its target gene, 11/February/2015, 23.07

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Web: http://genomediscovery.org Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Significance: This study suggests, for the first time, that MiRNA-7, by suppressing the expression of its […]
February 11, 2015

Molecular therapy for Inflammatory Bowel disease (IBD): PCBP2 preserves the functions of Beclin 1 and ATG5 and decreases tissue injury in inflammatory bowel disease (IBD) via down regulation of its target gene, 11/February/2015, 22.57

A study from Department of Medicine, University of Chicago, Chicago, Illinois, USA shows that “Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation.” This study was published in the […]
February 11, 2015

Regenerative stem cell therapy for Myocardial Infarction: BMP4 inhibits myocardial function after myocardial infarction via down regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 11/February/2015, 22.51

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the March 7  2013 issue of Nature  by Prof Dimmler, […]