February

February 7, 2015

Small molecule-based cancer therapy: Succinate, an intermediate in the TCA cycle, inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 7/February/2015, 11.03 am

A study from Karolinska Institutet, Stockholm, Sweden shows that MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.  This study was published in the April 10, 2014 Nature [I.F >42] by Prof. Thomas H, […]
February 7, 2015

MiRNA-based cancer therapy: MiRNA-98 inhibits cancer development by suppressing the expression of nucleotide sanitizing enzyme MTH1/NUDT1, 07/February/2015, 8.08 am

A study from Karolinska Institutet, Stockholm, Sweden shows that MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.  This study was published in the April 10, 2014 Nature [I.F >42] by Prof. Thomas H, […]
February 7, 2015

MiRNA-based therapy for cancer: ID-1 suppresses the expression of tumor suppressor TIMP3 via up regulation of its target gene, 7/February/2015, 07.59 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, MiRNA-based therapy for cancer: ID-1 suppresses the expression of tumor suppressor TIMP3 via up regulation of its […]
February 7, 2015

Natural product-based therapy for B-cell cancer: Cirsilol (3′,4′,5-trihydroxy-6,7-dimethoxyflavone), a flavone isolated from Achillea fragrantissima, suppresses the expression of FOXP1 and inhibits Wnt/β-catenin signalling via up regulation of its target gene, 07/February/2015, 07.55 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, Natural product-based therapy for B-cell cancer: Cirsilol (3′,4′,5-trihydroxy-6,7-dimethoxyflavone), a flavone isolated from Achillea fragrantissima,  suppresses the expression of FOXP1 […]