Natural product-based therapy for p53-mutated human cancers: Ursolic acid increases the expression of tumor suppressor p53 homologue TAp63 via down regulation of its target gene, 4/March/2015, 8.31 am

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Natural product-based therapy for p53-mutated human cancers: Ursolic acid increases  the expression of tumor suppressor p53 homologue TAp63 via down regulation of its target gene, 4/March/2015, 8.31 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: This study suggests, for the first time, that Ursolic acid, by decreasing the expression of its target gene, it may increase the expression of TAp63. Thereby, it may inhibit cancer progression. Thus, pharmacological formulations encompassing “Ursolic acid or its analogues”  can be used to inhibit the progression of human tumors

Amount: $ 300*

Undisclosed information: How Ursolic acid increases the expression of TAp63

Web: http://genomediscovery.org

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* Research cooperation

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