Anti-metastasis therapy: Tetraindole suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 23/March/2015, 22.05

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, L., Anti-metastasis therapy: Tetraindole suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 23/March/2015, 22.05, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: The study presented here suggests that Tetraindole, by increasing the expression of its target genes, it may suppress the expression of actin-regulatory proteins FHOD1 and PPM1F. Thereby, it may inhibit migration and invasion of metastatic cancer cells. Thus, pharmacological formulations encompassing “Tetraindole or its analogues” may be used to inhibit the progression of invasive tumors.

Undisclosed information: How Tetraindole  decreases the expression of FHOD1 and PPM1F

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