Anti-metastatic therapy: MiRNA-107 suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 29/March/2015, 21.33

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, L., Anti-metastatic therapy: MiRNA-107 suppresses the expression of actin-regulatory proteins FHOD1 and PPM1F and inhibits migration and invasion of metastatic cancer cells via up regulation of its target gene, 29/March/2015, 21.33, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: The study presented here suggests that MiRNA-107, by decreasing the expression of its target genes, it may suppress the expression of actin-regulatory proteins FHOD1 and PPM1F. Thereby, it may inhibit migration and invasion of metastatic cancer cells. Thus, pharmacological formulations encompassing “MiRNA-107 activators” may be used to inhibit the progression of invasive tumors.

Undisclosed information: How MiRNA-107 decreases the expression of FHOD1 and PPM1F

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