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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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Significance:  This study suggests, for the first time, Interleukin-37 (IL-37), by suppressing the expression of its target gene, it may increase the expression of tumor suppressor TIMP3. Thus, pharmacological formulations encompassing “IL-37 or its activators”  can be used to inhibit the progression of human tumors.

CitationBoominathan, Interleukin-based anti-cancer therapy: Interleukin-37 (IL-37) increases the expression of TIMP3 via down regulation of its target gene, 6/March/2015,  22.02, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Web: http://genomediscovery.org

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Undisclosed information: How IL-37 increases the expression of tumor suppressor TIMP3

Amount: $ 300*

* Research cooperation

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