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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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Significance:  This study suggests, for the first time, Interleukin-37 (IL-37), by increasing the expression of its target gene, it may suppress the expression of stem cell protein Oct-4. Thus, pharmacological formulations encompassing “IL-37 or its activators”  can be used to inhibit cancer stem cell proliferation.

CitationBoominathan, Interleukin-based anti-cancer therapy: Interleukin-37 (IL-37) suppresses the expression of stem cell protein Oct-4 via up regulation of its target gene, 22/March/2015, 22.28, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Web: http://genomediscovery.org

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Undisclosed information: How IL-37 decreases the expression of Stem cell protein Oct-4

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