Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Interleukin-based therapy for Cancer: Interleukin-1β suppresses the expression of RNA polymerase I via down regulation of its target gene, 15/March/2015, 08.16 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: This study suggests, for the first time, that Interleukin-1β, by suppressing the expression of its target gene, it may increase the expression of RNA polymerase I. Thereby, it may increase the proliferation of cancer cells. Thus, pharmacological formulations encompassing “Interleukin-1β activators” can be used to inhibit the progression of human cancers.
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Undisclosed information: How Interleukin-1β suppresses the expression of RNA polymerase I