Molecular therapy for Human Cancer: Roquin [RING finger and CCCH-type zinc finger domain-containing protein 1] increases the expression of tumor suppressor p53 and its target genes via down regulation of its target gene, 6/March/2015, 22.23

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org

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Significance: This study suggests, for the first time, that Roquin, by down regulation of its target gene, it may increase the expression of guardian of the genome, p53.  Thus, pharmacological formulations containing “Roquin activators” can be used in the treatment of human cancers.

To citeBoominathan,   Molecular therapy for Human Cancer: Roquin [RING finger and CCCH-type zinc finger domain-containing protein 1] increases the expression of tumor suppressor p53 and its target genes via down regulation of its target gene, 6/March/2015, 22.23,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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* Research cooperation

Undisclosed information: How Roquin increases the expression of p53

Amount: $300*

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