Life-span extension therapy: LIF inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 23/March/2014, 15.05

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, L., Life-span extension therapy: LIF inhibits senescence and  extends life span by down regulating the expression of  adenylate cyclase 5 (ADCY5), 23/March/2014, 15.05, Genome-2-Bio-Medicine Discovery center (GBMD),


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Significance: This study suggests, for the first time, that LIF, by increasing he expression of its target gene, it may suppress the expression of ADCY5/AC5 expression. Thus, pharmacological formulations encompassing “LIF activators may be used to extend the life-span of an an individual.

Undisclosed information: How LIF suppresses the expression of  adenylate cyclase 5 (ADCY5)

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