Natural product-based Life-span extension therapy: Hesperitin, a natural compound isolated from citrus fruits, inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 08/March/2014, 22.40

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, L., Natural product-based Life-span extension therapy: Hesperitin, a natural compound isolated from citrus fruits, inhibits senescence and  extends life span by down regulating the expression of  adenylate cyclase 5 (ADCY5), 08/March/2014, 22.39, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests, for the first time, that Hesperitin may extend the lifespan of an individual by suppressing ADCY5/AC5 expression. Thus, pharmacological formulations encompassing “Hesperitin or its analogues” may be used to extend the lifespan of an an individual.

Undisclosed information: How Hesperitin suppresses the expression of  adenylate cyclase 5 (ADCY5)

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