March

March 26, 2015

Molecular therapy for Metabolic diseases: TAp63 increases MiRNA-143/145 levels and decreases angiotensin-converting enzyme (ACE)-expression via up regulation of AMPKα2, 26/March/2015, 10.24

Significance: This study suggests, for the first time, that TAp63, by increasing the expression of its target genes AMPKα2 and MiRNA-143/145, it may decrease the expression of angiotensin-converting […]
March 26, 2015

Small molecule-based Life-span extension therapy: BRCA1 inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 26/March/2014, 9.58 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ Citation: Boominathan, L., Small molecule-based Life-span extension therapy: BRCA1 inhibits senescence and  extends life span by down regulating the […]
March 25, 2015

Natural product-based therapy for hypoxia/inflammation-associated brain damage: Oleic acid (OA), the major component of Neem Oil, decreases infarct size, edema formation, neutrophil infiltration and promotes neuronal survival via down regulation of TIM-3, 25/March/2015, 22.31

A recent study from the Cancer Immunology Branch, Department of System Cancer Science, National Cancer Center, 111 jungbalsan-ro, Kyunggi 410-769, Republic of Korea; and Department of Physiology, Development […]
March 25, 2015

MiRNA-based therapy for Fibrosis: Endothelin-1 suppresses TGFβ-dependent extracellular matrix accumulation and fibrosis via up regulation of its target gene, 25/March/2015, 22.28

A recent study from the Center for Cardiovascular and Pulmonary Research and Heart Center, Nationwide Children’s Hospital, Department of Pediatrics, The Ohio State University, Columbus shows that “MicroRNA miR145 […]