Regenerative Stem cell therapy for Myocardial Infarction: MiRNA-214 improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 07/March/2015, 16.12

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A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Regenerative Stem cell therapy for Myocardial Infarction: MiRNA-214 improves myocardial function after myocardial infarction via  up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10). By increasing the expression of MiRNA-638 in cardiomyocytes, one may prevent ageing-associated (or, prolonged stress-associated) decline in cardiac function. Together, this study suggests that pharmacological formulations encompassing “MiRNA-214 activators” may be used to improve cardiac function after myocardial infarction.

Idea Proposed/Formulated byDr L Boominathan Ph.D.

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To citeBoominathan, Regenerative Stem cell therapy for Myocardial Infarction: MiRNA-214 improves myocardial function after myocardial infarction via  up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 07/March/2015,  16.12,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Undisclosed information: How MiRNA-214  increases the expression of PNUTS/PPP1R10

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