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April 30, 2015

The Exercise-Mimicking pills may inhibit Insulin resistance and decrease adiposity: BMB4 decreases gluconeogenesis genes, such as PEPCK and G6Pase, reduces hepatic glucose production, improves muscle insulin sensivitity and decreases adiposity via up regulation of its target gene, 1/May/2015, 12.19 am

Significance: This study suggests, for the first time, that BMP4, by increasing the expression of its target gene, it may: (1) decrease the expression of gluconeogenesis genes, such […]
April 30, 2015

Turning on senescence turns off cancer progression: HIF-1α inhibits telomere dysfunction and senescence via up regulation of Telomeric repeat binding factor 2 (TRF2), 30/April/2015, 23.57

A recent study from the Key Laboratory of Gene Engineering of the Ministry of Education, Key Laboratory of Reproductive Medicine of Guangdong Province, School of Life Sciences […]
April 30, 2015

Natural product-based therapy for Regenerating the lost cardiomyocytes in Myocardial patients: SNAI, an activator of epithelial-mesenchymal transition, increases the expression of ERBB2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 30/April/2014, 23.37

A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
April 30, 2015

Molecular therapy for wound healing: Succinate, one of the component in the TCA cycle, enhances skin wound healing and attenuates pathological scarring via down regulation of its target gene, 30/April/2014, 23.23

A recent study from the Department of Pathology, School of Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan shows that “Reduced FOXO1 expression accelerates skin wound […]