A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School of Medicine, The University of New South Wales, Australia shows that Sirtuin-2 induces the checkpoint kinase BubR1 to increase lifespan. This study was published in the 1 July 2014 issue of the journal “EMBO” by Prof Sinclair, North BJ, and others.
On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-based Lifespan extension therapy: Epigallocatechin gallate, the main component of Green tea, increases life span via up regulation of its target gene BubR1. Thus, pharmacological formulations encompassing “Epigallocatechin gallate or its analogues” may be used to extend the lifespan of an individual.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Undisclosed information: How Epigallocatechin gallate increases the expression of BubR1
To cite: Boominathan, Natural product-based Lifespan extension therapy: Epigallocatechin gallate, the main component of Green tea, increases life span via up regulation of its target gene BubR1, 6/April/2015, 16.46, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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