Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, MiRNA-based Anti-ageing therapy: MiRNA-146a increases the expression of immortality gene telomerase via down regulation of its target genes, 28/April/2015, 22.50, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: It has been shown earlier that transgenic expression of telomerase increases the longevity of mice. This study suggests, for the first time, that MiRNA-146a, by decreasing the expression of its target gene, it may increase the expression of immortality gene telomerase. Thereby, it may increase the life-span of an individual. Thus, pharmacological formulations encompassing “MiRNA-146a activators” can be used to decrease ageing and increase the life-span of an individual.
Undisclosed information: How MiRNA-146a increases the expression of immortality gene telomerase
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