MiRNA-based Anti-ageing therapy: MiRNA-146a increases the expression of immortality gene telomerase via down regulation of its target genes, 28/April/2015, 22.50

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, MiRNA-based Anti-ageing therapy: MiRNA-146a increases the expression of immortality gene telomerase via down regulation of its target genes, 28/April/2015, 22.50, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: It has been shown earlier that transgenic expression of telomerase increases the longevity of mice. This study suggests, for the first time, that MiRNA-146a, by decreasing the expression of its target gene, it may increase the expression of immortality gene telomerase. Thereby, it may increase the life-span of an individual. Thus, pharmacological formulations encompassing “MiRNA-146a activators”  can be used to decrease ageing and increase the life-span of an individual.

Undisclosed information: How MiRNA-146a increases the expression of immortality gene telomerase

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