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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, L., Molecular therapy for cancer: Triptolide, found in the herb Thunder of God Vine, inhibits cellular proliferation, invasion and metastasis via down regulation of  Frizzled7 receptor (FZD7), 16/May/2015, 23.24, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: 

This suggests that Triptolide, by increasing the expression of its target gene, it may decrease the expression of Frizzled7 receptor (FZD7).  Thereby, it may inhibit proliferation, invasion and metastasis. Thus, pharmacological formulations encompassing Triptolide or its analogues may be used to inhibit the progression of tumors.

Undisclosed information: How Triptolide decreases the expression of Frizzled7 receptor (FZD7)

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