Small molecule-based Lifespan extension therapy: ARA-A, an antiviral drug, inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 9/May/2015, 8.36 am

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, L., Small molecule-based Lifespan extension therapy: ARA-A, an antiviral drug, inhibits senescence and  extends life span by down regulating the expression of  adenylate cyclase 5 (ADCY5), 9/May/2015, 8.35 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study suggests, for the first time, that ARA-A may extend the lifespan of an individual by suppressing ADCY5/AC5 expression. Thus, pharmacological formulations encompassing “ARA-A  or its analogues may be used to extend the life-span of an an individual.

Undisclosed information: How ARA-A suppresses the expression of  adenylate cyclase 5 (ADCY5)

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