Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, L., Small RNAs as Lifespan extenders: MiRNA-224 inhibits senescence and extends life span by down regulating the expression of adenylate cyclase 5 (ADCY5), 17/May/2015, 09.15 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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Significance: This study suggests, for the first time, that MiRNA-224, by suppressing the expression of its target gene, may decrease the expression of ADCY5/AC5. Thereby, it may increase the lifespan of an individual. Thus, pharmacological formulations encompassing “MiRNA-224 or its activators“ may be used to extend the life-span of an individual.
Undisclosed information: How MiRNA-224 suppresses the expression of adenylate cyclase 5 (ADCY5)