Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
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Citation: Boominathan, Natural product-based Anti-ageing therapy: Kaempherol, found in leeks, apples, and onions, increases the expression of immortality gene telomerase via down regulation of its target genes, 13/June/2015, 11.36 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Significance: It has been shown earlier that transgenic expression of telomerase increases the longevity of mice. This study suggests, for the first time, that Kaempherol, by decreasing the expression of its target gene, it may increase the expression of (1) immortality gene telomerase; and (2) the longevity-promoting gene Sirtuin-1. Thereby, it may increase the life-span of an individual. Thus, pharmacological formulations encompassing “Kaempherol or its analogues” can be used to decrease ageing and increase the life-span of an individual.
Undisclosed information: How Kaempherol increases the expression of immortality gene telomerase
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