A known drug of an unknown anti-viral function: Metformin, the widely used drug in the treatment of T2DM, suppresses dengue virus replication via up regulation of its target gene, 8/June/2015, 6.19 pm

Regenerating the lost pancreatic β-cells in DM patients: MiRNA-196a increases insulin-secreting cell mass and function via down regulation of its target genes, 8/June/2015, 6.00 pm
June 8, 2015
Natural product-based anti-viral therapy: Cirsilol(3′,4′,5-trihydroxy-6,7-dimethoxyflavone), a flavone isolated from Achillea fragrantissima, suppresses porcine reproductive and respiratory syndrome virus infection via up regulation of its target gene, 8/June/2015, 10.35 pm
June 8, 2015
Show all

Idea Proposed/Formulated byDr L Boominathan Ph.D.

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

CitationBoominathan, L., A known drug of an unknown anti-viral function: Metformin, the widely used drug in the treatment of T2DM, suppresses dengue virus replication via up regulation of its target gene, 8/June/2015, 6.19 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Significance: 

This suggests, for the first time, that Metformin, by decreasing the expression of its target gene, it may suppress dengue virus replication.  Thus, pharmacological formulations encompassing “Metformin or its analogues may be used to inhibit dengue virus replication.

Undisclosed information: How Metformin inhibits dengue virus replication.

Web: http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

* Research cooperation

Comments are closed.