Monthly Archives: July 2016

Amino acid therapy for Diabetes mellitus: Taruine increases islet insulin levels, islet cell mass and glucose tolerance via down regulation of NMDA receptor GluN2A, 28/July/2016, 8.23 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Undisclosed information: How Taurine decreases the expression of NMDA receptor GluN2A Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ A study from the Institute of Metabolic Physiology, Heinrich Heine University, Düsseldorf, Germany shows that: “Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.” This study was … Continue reading

Posted in Ideas | Comments Off on Amino acid therapy for Diabetes mellitus: Taruine increases islet insulin levels, islet cell mass and glucose tolerance via down regulation of NMDA receptor GluN2A, 28/July/2016, 8.23 am

Natural product-based therapy for Bone disorders: Genistein inhibits osteoporosis and bone metastasis via up regulation of its target gene, 28/July/2016, 7.45 am

A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.” This study was published in the June 25, 2014 Nature  [I.F >42] by Prof. Wan Y, Krzeszinski and … Continue reading

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Natural product-based Lifespan extension therapy: Berberine activates autophagy and extends lifespan via up regulation of ATG5, 26/July/2016, 8.44 am

A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was published in the online journal “Nature communications” by Prof. Jung YK, Pyo Jo and others.  On the foundation of this interesting … Continue reading

Posted in Ideas | Tagged | Comments Off on Natural product-based Lifespan extension therapy: Berberine activates autophagy and extends lifespan via up regulation of ATG5, 26/July/2016, 8.44 am

Interleukin therapy for Diabetes mellitus: IL-17 increases islet insulin levels, islet cell mass and glucose tolerance via down regulation of NMDA receptor GluN2A, 24/July/2016, 7. 04 am

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Undisclosed information: How IL-17 decreases the expression of NMDA receptor GluN2A Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ A study from the Institute of Metabolic Physiology, Heinrich Heine University, Düsseldorf, Germany shows that: “Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.” This study was … Continue reading

Posted in Ideas | Comments Off on Interleukin therapy for Diabetes mellitus: IL-17 increases islet insulin levels, islet cell mass and glucose tolerance via down regulation of NMDA receptor GluN2A, 24/July/2016, 7. 04 am

Small molecule-based therapy for Intestinal cancer: UBTD1 increases the expression of DNA Sensor AIM2 and inhibits expansion of tumor-initiating intestinal stem cell population via up regulation of its target gene, 23/July/2015, 11.40 pm

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Undisclosed information: How UBTD1  increases the expression of tumor suppressor AIM2. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ A recent study from the Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA shows that:  “Critical Role for the DNA Sensor AIM2 … Continue reading

Posted in Ideas | Comments Off on Small molecule-based therapy for Intestinal cancer: UBTD1 increases the expression of DNA Sensor AIM2 and inhibits expansion of tumor-initiating intestinal stem cell population via up regulation of its target gene, 23/July/2015, 11.40 pm

Small RNA-based therapy for pulmonary arterial hypertension: MiRNA-7 inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 23/July/2015, 11.14 pm

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in General Medicine with an I.F of 28.054] by Prof. Thistlethwaite PA, Li X and others. On the foundation of … Continue reading

Posted in Ideas | Comments Off on Small RNA-based therapy for pulmonary arterial hypertension: MiRNA-7 inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 23/July/2015, 11.14 pm

Regenerative Stem cell therapy for Myocardial Infarction: MiRNA-290 improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 23/July/2016, 14.35

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Regenerative … Continue reading

Posted in Ideas | Comments Off on Regenerative Stem cell therapy for Myocardial Infarction: MiRNA-290 improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 23/July/2016, 14.35