Monthly Archives: August 2016

MiRNA-497 inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via down regulation of its target gene, 7/August/2016, 3.35 pm

A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.” This study was published in the 2 October 2009 … Continue reading

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MiRNA therapy for Intestinal cancer: MiRNA-1976 increases the expression of DNA Sensor AIM2 and inhibits expansion of tumor-initiating intestinal stem cell population via up regulation of its target gene, 7/August/2016, 3.24 pm

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Undisclosed information: How MiR-1976  increases the expression of tumor suppressor AIM2. Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/ A recent study from the Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA shows that:  “Critical Role for the DNA Sensor AIM2 … Continue reading

Posted in Ideas | Comments Off on MiRNA therapy for Intestinal cancer: MiRNA-1976 increases the expression of DNA Sensor AIM2 and inhibits expansion of tumor-initiating intestinal stem cell population via up regulation of its target gene, 7/August/2016, 3.24 pm

Small RNA-based therapy for pulmonary arterial hypertension: MiRNA-491-5p inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 7/August/2016, 2.58 pm

A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in General Medicine with an I.F of 28.054] by Prof. Thistlethwaite PA, Li X and others. On the foundation of … Continue reading

Posted in Ideas | Comments Off on Small RNA-based therapy for pulmonary arterial hypertension: MiRNA-491-5p inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 7/August/2016, 2.58 pm

Small ribonucleic acid medicine therapy for Myocardial Infarction: MiRNA-520/373 improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 7/August/2016, 1.41 pm

A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Small … Continue reading

Posted in Ideas | Comments Off on Small ribonucleic acid medicine therapy for Myocardial Infarction: MiRNA-520/373 improves myocardial function after myocardial infarction via up regulation of PNUTS/PPP1R10 (Serine/threonine-protein phosphatase 1 regulatory subunit 10), 7/August/2016, 1.41 pm