Natural product Life-span extension therapy: Carnosic acid (CA), isolated from Rosemary (Rosemarinus officinalis), increases life span by suppressing mTOR pathway through up regulation of its target gene, 27/September/2016, 9.33 pm

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Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org or http://newbioideas.com

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 Significance:  

This study suggests, for the first time, that Carnosic acid, isolated from Rosemary, by suppressing the expression of mTOR, it may: (i) increase autophagic flux; (ii) decrease reactive oxygen species; and (iii) increase  the lifespan of an individual. Of interest, decreasing the expression/activity of mTOR has earlier been shown to increase overall lifespan. Together, this study 

rosmarinus_officinalis1

Carnosic acid, isolated from Rosemary, may function as a longevity promoter via down regulation of mTOR

suggests that pharmacological formulations encompassing “Carnosic acid or its analogues” may function as longevity promoters.

CitationBoominathan, L., Natural product Life-span extension therapy: Carnosic acid (CA), isolated from Rosemary (Rosemarinus officinalis), increases life span by suppressing mTOR pathway through up regulation of its target gene, 27/September/2016, 9.31 pm,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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# Research cooperation

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