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A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.”

This study was published in the June 25, 2014 Nature  [I.F >42] by Prof. Wan Y, Krzeszinski and others from  the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Vitamin therapy for Bone disorders: Delta-tocotrienol, the Vitamin-E, inhibits osteoporosis and bone metastasis via up regulation of its target gene.  

This study may suggest that Delta-tocotrienol, by up regulating its target gene, it may suppress the expression of Tgif2. Together, this study suggests that pharmacological formulations encompassing Delta-tocotrienol or its analogues” can be used to inhibit osteoporosis and bone metastasis. 

Idea Proposed/Formulated by: Dr L Boominathan PhD

Amount: $100#

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CitationBoominathan, Vitamin therapy for Bone disorders: Delta-tocotrienol, the Vitamin-E, inhibits osteoporosis and bone metastasis via up regulation of its target gene, 18/September/2014, 10.23 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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