Immune enhancement therapy: Bone morphogenetic protein 2 (BMP2) increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 25/October/2016, 7.56 pm

Molecular therapy for Breast Cancer: TRIM protein DEAR1/TRIM62 increases the level of tumor suppressor p53, inhibits the proliferation of tumor-initiating cells in breast cancer, suppresses the progression of metastatic breast cancer, and supports tumor relapse-free survival in breast cancer patients, 25/October/2015, 7.20 am
October 25, 2016
Natural product therapy for Diabetes mellitus: Sulforaphane, found in Brussels Sprouts, Broccoli, Cabbage, Cauliflower, Kale, among others, increases islet insulin levels, islet cell mass and glucose tolerance via down-regulation of NMDA receptor GluN2A, 25/October/2016, 8.34 am
October 25, 2016
Show all

A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate immunity against microbial infection.” This study was published in the 2 March 2015 issue of the Journal “Nature Immunology” [the number one journal in immunological research with an impact factor of  24.973] by Drs. Zusen Fan, Xia and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Immune enhancement therapy: Bone morphogenetic protein 2 (BMP2) increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene. 


Research findings

This study suggests, for the first time, BMP2, by decreasing the expression of its target gene, it may : (1) increase the expression of Sox2; (2) increase the ability of Sox2 to recognize bacterial DNA in cytoplasm; and (3) promote innate immunity against bacterial infection. Together, pharmacological formulations encompassing BMP2 activators may be used to (1) enhance innate immunity against bacterial infection; and (2) promote bacterial resistance. 


Idea Proposed, with factual evidence, byDr L Boominathan Ph.D.

Web: http://genomediscovery.org or http://newbioideas.com

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

CitationBoominathan, L., Immune enhancement therapy: Bone morphogenetic protein 2 (BMP2) increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 25/October/2016, 7.56 pm,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

# Research cooperation


Undisclosed information: How BMP2: (1) enhances innate immunity against bacterial infection; and (2) promotes bacterial resistance?

Amount: $200

satisfaction-guaranted-if-not-refunded

Results-guaranteed-if-not-refunded

Comments are closed.