Natural product-based Combination therapy for Lifespan extension: Green tea extract and Curcumin combo increases life span via up-regulation of its target gene BubR1, 27/October/2016, 2.54 pm

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 What they say: Introduction: 

A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School of Medicine, The University of New South Wales, Australia shows that Sirtuin-2 induces the checkpoint kinase BubR1 to increase lifespan. This study was published in the 1 July  2014 issue of the journal  “EMBO” by Prof Sinclair, North BJ, and others.

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Natural product Lifespan extension therapy: Green tea extract and Curcumin combo  increases life span via up-regulation of its target gene BubR1. 


What we say: Research Findings: 

This study suggests a natural product-based life extension therapy. 

Isorhapontigenin, isolated from  Aiphanes Aculeata, Norway/Sitka/White Spruce ,  among others, extends mammalian lifespan via up-regulation of BuBR1

Turmeric. Curcumin, isolated from  Turmeric, extends mammalian lifespan via up-regulation of BuBR1

Turmeric

Turmeric. Curcumin, isolated from Turmeric, slows down aging and increases median lifespan via up-regulation of BuBR1

Green tea extract + Turmeric: A recipe for Life-span extension: Superinduction of BuBR1 by Green tea extract and Curcumin combo may extend life span.

 

Green

Green tea leaves:  Green tea slows down aging and increases median lifespan via up-regulation of BuBR1

Green tea extract and Curcumin combo, by increasing the expression of its target gene BuBR1, it may: (1) delay diseases of ageing; (2) slow down aging; and (3) prolong median life span. Thus, pharmacological formulations encompassing Green tea extract and Curcumin combo may be used to extend the lifespan of an individual. 


Idea Proposed/Formulated byDr L Boominathan Ph.D.

Web: http://genomediscovery.org or http://newbioideas.com

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CitationBoominathan, Natural product-based Combination therapy for Lifespan extension: Green tea extract and Curcumin combo increases life span via up-regulation of its target gene BubR1, 27/October/2016, 2.54 pm,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org


Undisclosed information: How Green tea extract and Curcumin combo increases the expression of BubR1 and extends mammalian life-span

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