Anti-metastasis therapy: Tumor suppressor ING1b/p33 decreases PDPN expression, invasion, migration and metastasis of tumor cells via up regulation of its target gene, 27/November/2015, 8.16 pm

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Research findings to Therapeutic opportunity: 

The study presented here suggests that tumor suppressor ING1b/p33, by increasing the expression of its target genes, it may decrease the expression of oncoprotein PDPN.

price-2

Thereby, it may inhibit proliferation, migration, invasion,  and metastasis of cancer cells. Thus, pharmacological formulations encompassing ING1b/p33 activators” may be used to inhibit the progression of invasive tumors.


Details of the research findings

Idea Proposed/Formulated (with experimental evidence) by:

Dr L Boominathan Ph.D.

Undisclosed information: How tumor suppressor ING1b/p33 decreases the expression of metastasis suppressor PDPN

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References

CitationBoominathan, L., Anti-metastasis therapy: Tumor suppressor ING1b/p33 decreases PDPN expression, invasion, migration and metastasis of tumor cells via up regulation of its target gene, 27/November/2015, 8.16 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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