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What we say:

Dr L Boominathan PhD, Director-cum-chief Scientist of GBMDreports here that:  Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extends lifespan via up regulation of its target gene

[easy_payment currency=”USD”]price-100


From Significance of the study to Therapeutic opportunity:

This study suggests, for the first time, that Lithocholic acid (LCA), by increasing the expression of its target gene, it may: (1) enhance autophagy, (2) promote leanness; (3) increase insulin sensitivity; (4) improve motor function; (5) increase resistance to oxidative stress; (6) alleviate ageing features; and (7) promote longevity( fig.1).

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Figure 1. Lithocholic acid enhances autophagy, increases insulin sensitivity and promotes longevity via up regulation of its target gene

Thus, pharmacological formulations encompassing “Lithocholic acid (LCA) or its analogues or Lithocholic acid plus any of the known anti-ageing compoundsmay be used to increase the life span of an individual.


Details of the research findings

Idea Proposed/Formulated byDr L Boominathan PhD

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Amount: $ 100

Undisclosed mechanistic information: How does Lithocholic acid activate autophagy and extend lifespan?

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References:

Web: http://genomediscovery.org or newbioideas.com

CitationBoominathan, L., Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extend lifespan via up regulation of its target gene, 2/December/2016, 7.04am

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