Natural product-derived Life-span extension therapy: Ginsenoside 20(S)-Rg3, one of the main components of Panax ginseng, activates autophagy and extends lifespan via up regulation of its target gene, 5/December/2016, 7. 31 pm

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What we say:

Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that: Ginsenoside 20(S)-Rg3, one of the main components of Panax ginseng, activates autophagy and extends lifespan via up regulation of its target gene

[easy_payment currency=”USD”]price-100


From Significance of the study to Therapeutic opportunity:

This study suggests, for the first time, that Ginsenoside 20(S)-Rg3, by increasing the expression of its target gene, it may: (1) enhance autophagy, (2) promote leanness; (3) increase insulin sensitivity; (4) improve motor function; (5) increase resistance to oxidative stress; (6) alleviate ageing features; and (7) promote longevity( fig.1 &2).

Figure 1. Panax ginseng

Figure 1. Panax ginseng. Ginsenoside 20(S)-Rg3, isolated from Panax ginseng, enhances autophagy, increases insulin sensitivity and promotes longevity via up regulation of its target gene

Thus, pharmacological formulations encompassing “Ginsenoside 20(S)-Rg3 or its analogues or Ginsenoside 20(S)-Rg3 plus any of the known anti-ageing compoundsmay be used to increase the life span of an individual.

Ginsenoside 20(S)-Rg3 க்கான பட முடிவு

Figure 2. Ginsenoside 20(S)-Rg3


Details of the research findings

Idea Proposed/Formulated byDr L Boominathan PhD

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Amount: $ 100

Undisclosed mechanistic information: How does  Ginsenoside 20(S)-Rg3 activate autophagy and extend lifespan?

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References:

Web: http://genomediscovery.org or newbioideas.com

CitationBoominathan, L., Natural product-derived Life-span extension therapy: Ginsenoside 20(S)-Rg3, one of the main components of Panax ginseng,   activates autophagy and extends lifespan via up regulation of its target gene, 5/December/2016, 7. 31 pm

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