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February 22, 2017

Anti-telomerase cancer therapy: USP13 (Ubiquitin Specific Peptidase 13)/Isopeptidase T-3 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and the cellular immortality gene telomerase and inhibits cancer progression via down-regulation of it target gene, 22/February/2017, 11. 12 pm

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]
February 22, 2017

Natural product-based therapy for Metastatic cancers: (6)-gingerol (6G), one of the main components of Ginger, increases the expression of CCM1/KRIT1 and promotes apoptosis, inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 22/February/2017, 10.58 pm

Research findings to Therapeutic opportunity:  The study presented here suggests that (6)-gingerol (6G), by increasing the expression of its target genes, it may increase the expression of […]
February 22, 2017

Vitamin therapy for Diabetic Kidney disease: Ascorbate, found abundantly in yellow pepper and amla among others, decreases VEGF-B expression, inhibits lipid accumulation in Podocytes, promotes insulin signalling in Podocytes, induces insulin sensitivity, ameliorates renal dysfunction and alleviates diabetic kidney disease via down regulation of its target gene, 22/February/2017, 2.02 pm

Introduction: What they say A study from the Division of Vascular Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden shows that […]
February 22, 2017

Natural product-derived antiviral therapy against HIV virus: γ-Bisabolene, one of the components in Cardamom, Cubeb, lemon, and Oregano among others,increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 22/February/2017, 10.31 am

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]