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Research findings to Therapeutic opportunity: 

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The study presented here suggests that (6)-gingerol (6G), by increasing the expression of its target genes, it may increase the expression of BTG2. Thereby, it may promote apoptosis, inhibit migration, invasion and metastasis of cancer cells. Thus, pharmacological formulations encompassing “(6)-gingerol (6G) or its analogues” may be used to inhibit the progression of invasive tumors.


Details of the research findings

Idea Proposed/Formulated (with experimental evidence) by:

Dr L Boominathan Ph.D.

Undisclosed information: How (6)-gingerol (6G) increases the expression of metastasis suppressor BTG2

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References: 

CitationBoominathan, L., Natural product-based therapy for Metastatic cancers: (6)-gingerol (6G), one of the main components of Ginger, increases the expression of BTG2 and promotes apoptosis, inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 21/February/2017, 11.16 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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