February 2, 2017

Natural product-derived therapy for Metastatic human tumors: Brusatol, found in Brucea javanica (L) Merr. (Simaroubaceae), decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 2/February/2017, 10.39 pm

Introduction: What they say: A study from the State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen […]
February 2, 2017

Immune enhancement therapy: IFN-I increases SOX2 expression and promotes innate immunity against bacterial infection via down-regulation of its target gene, 2/January/2017, 10.45 am

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]
February 2, 2017

Natural product-based therapy for Metastatic tumors: Formononetin, an isoflavone found in the roots of astragalus membranaceus, Trifolium pratense, Glycyrrhiza glabra, and Pueraria lobata, increases the expression of metastasis suppressor gene TIMP-3 and inhibits invasion, migration and metastasis of tumor cells via down regulation of its target gene, 2/February/2017, 10.35 pm

From Significance of the study to Public health relevance:  Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
February 1, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Howthorn extract increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 1/February/2017, 11.59 pm

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]