05

March 5, 2017

Molecular therapy for Bone disorders: Linalool, one of the main components of Coriander seeds and Lamiaceae among others, inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via down-regulation of its target gene, 6/March/2017, 12.06 am

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone […]
March 5, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Fucosterol, isolated from brown alga, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 6/March/2017, 12.07 am

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
March 5, 2017

Natural product-derived antiviral therapy for HIV virus: Bergapten, found in Bergamot, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 5/March/2017, 11.30 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
March 5, 2017

Natural product-based therapy for Metastatic cancers: Hyperoside, isolated from Drosera rotundifolia, and Common self-heal, among others, increases the expression of KRIT1/CCM1 and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 5/March/2017, 10.54 pm

Research findings to Therapeutic opportunity:  A number of studies suggest that Hyperoside functions as an anticancer agent. However, the mechanism of action is far from clear. […]