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March 8, 2017

Natural product-derived antiviral therapy for HIV virus: Luteolin-7-O-glucoside (LUTG), isolated from Dracocephalum tanguticum Maxim, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 8/March/2017, 3.29 pm

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
March 8, 2017

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: ADAR1 (Adenosine deaminase acting on RNA1) increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene, 8/March/2017, 10.54 am

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The […]
March 8, 2017

Natural product-derived therapy for Metastatic cancers: Curcumin, one of the main components of turmeric, decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 8/March/2017, 9.34 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
March 8, 2017

Molecular therapy for triple-negative breast tumors: PAPD5 (PAP-Associated Domain-Containing Protein 5/(Poly(A) RNA Polymerase D5, Non-Canonical) increases the levels of cell cycle inhibitor, p27, inhibits pro-survival pathways mediated by c-Myc, and inhibits the progression of triple-negative breast cancer via up-regulation of its target gene, 8/March/2017, 8.25 am

Introduction: What they say  A study from the Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA shows that […]