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March 21, 2017

MiRNA-based Life-span extension therapy: MiR-497 may increase lifespan by suppressing mTOR pathway, 21/March/2016, 11.59 pm

What is known:  It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity […]
March 21, 2017

Natural product-derived therapy for pulmonary fibrosis: Fla-CN, a flavonoid derivative of tiliroside, decreases miR-34 expression, increases Sirtuin-1 expression, suppresses tumor suppressor p53 acetylation, prevents apoptosis in Alveolar epithelial cell (AEC), and improves pulmonary fibrosis via down regulation of its target gene, 21/March/2017, 11.54 pm

What we say:  Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for pulmonary fibrosis: Fla-CN, a  flavonoid derivative of tiliroside,  decreases miR-34 expression, increases […]
March 21, 2017

Natural product-based Lifespan extension therapy: Justicidin A (JA) activates autophagy and extends lifespan via up regulation of ATG5, 21/March/2017, 11.42 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
March 21, 2017

Natural product-derived therapy for Allergic rhinitis: Linalool, found in coriander leaves, and laurel among others, inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, and eotaxin expression, among others, inhibits mucus production and alleviates allergic rhinitis via up regulation of its target gene, 21/March/2017, 11.37 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for Allergic rhinitis: Linalool, found in coriander leaves, and laurel […]