What is known:
It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity promoters.”
From research findings to therapeutic opportunity:
This study suggests that MiR-497, by suppressing the expression of mTOR, it may: (i) increase autophagic flux; (ii) decrease reactive oxygen species; and (iii) increase the lifespan of an individual.
Details of the research findings:
Dr L Boominathan Ph.D.
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# Research cooperation
Citation: Boominathan, L., MiRNA-based Life-span extension therapy: MiR-497 may increase lifespan by suppressing mTOR pathway, 21/March/2016, 11.59 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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