MiRNA-based Life-span extension therapy: MiR-761 may increase lifespan by suppressing mTOR pathway, 19/March/2016, 7.49 am

Natural product-derived therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Berberine, one of the major components of Berberis, Berberis aristata, Oregon grape, Hydrastis canadensis, and Phellodendron amurense, among others, promotes an insulin-sensitized state via up-regulation of its target gene Lin-28, 18/March/2017, 10.04 am
March 18, 2017
Natural product-derived antiviral therapy for HIV virus: Triptolide, isolated from herb Thunder God Vine, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 19/March/2017, 8.24 pm
March 19, 2017
Show all

What is known

It has been shown earlier that decreasing the expression/activity of mTOR increases overall mammalian lifespan, suggesting that mTOR inhibitors may function as “longevity promoters.” 


From research findings to therapeutic opportunity

This study suggests that MiR-761, by suppressing the expression of mTOR, it may: (i) increase autophagic flux; (ii) decrease reactive oxygen species; and (iii) increase  the lifespan of an individual. 


Details of the research findings

Idea Proposed/Formulated (with experimental evidence) by:Price 2

 

[easy_payment currency=”USD”]

Dr L Boominathan Ph.D.

Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/

Amount: $2#

For purchase and payment details, you may reach us at admin@genomediscovery.org

# Research cooperation


References:

Web: http://genomediscovery.org or http://newbioideas.com

CitationBoominathan, L., MiRNA-based Life-span extension therapy: MiR-761 may increase lifespan by suppressing mTOR pathway, 19/March/2016, 7.49 am,  Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

Courtesy: When you cite drop us a line at info@genomediscovery.org

Comments are closed.