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Introduction: What they say

A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was published in the online journal “Nature communications” by Prof. Jung YK, Pyo Jo and others. 


What we say

On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMDreports that: Natural product-based Lifespan extension therapy: Catalpol activates autophagy and extends lifespan via up regulation of ATG5


From research findings to therapeutic opportunity

This study suggests, for the first time, that Catalpol, by increasing the expression of its target gene ATG5, it may: (1) enhance autophagy, (2) promote leanness; (3) increase insulin sensitivity; (4) improve motor function; and (5) alleviate ageing features.

price-50[easy_payment currency=”USD”]

Thus, pharmacological formulations encompassing “Catalpol or its analogs either alone or in combination with other drugsmay be used to increase the life span of an individual (fig. 1).

Catalpol skeletal.svg

Figure 1. Catalpol functions as a longevity-promoter by increasing the expresison of ATG5


Details of the research findings

Idea Proposed/Formulated byDr L Boominathan PhD

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# Research cooperation


References

Web: http://genomediscovery.org or newbioideas.com/

Citation: Boominathan, L., Natural product-based Lifespan extension therapy: Catalpol activates autophagy and extends lifespan via up regulation of ATG5, 22/March/2017, 11.17 pm

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