It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R (AGTR1) gene results in marked prolongation of mammalian lifespan.
From research findings to therapeutic opportunity:
This study suggests, for the first time, that Hydrogen-rich water therapy, by increasing the expression of its target genes, it may decrease the expression of AT1R.
And, thereby, it may: (1) decrease blood pressure; (2) decrease blood sugar levels; (3) inhibit pulmonary fibrosis; (4) enhance bacterial immunity; (5) inhibit myocardial infarction; (6) increase telomerase expression, and decelerate ageing process; and (4) extend the lifespan of an individual.
Thus, physicians may consider encouraging their patients to drink Hydrogen-rich water to lead a healthy and long-life. Taken together, Hydrogen-rich water therapy may be used to extend the lifespan of an individual (Figure 1).
Details of the research findings:
Idea Proposed/Formulated by:
Dr L Boominathan Ph.D.
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
Undisclosed mechanistic information: How does Hydrogen-rich water suppress the expression of angiotensin II type I receptor (AT1R)?
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# Research cooperation
Citation: Boominathan, L., Hydrogen-rich water therapy for Lifespan extension: Hydrogen-rich water therapy prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 8/June/2017, 11.59 pm, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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