June

June 4, 2017

Natural product-derived regenerative therapy for reversing diabetes:Celastrol, isolated from Thunder God vine, increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 4/June/2017, 11.58 pm

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, […]
June 4, 2017

Natural product-derived PD-1 pathway activation for Pain therapy: Berberine increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 4/June/2017, 11.57 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
June 4, 2017

Natural product-derived therapy for Metastatic cancers: Schisandrin B decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 4/June/2017, 11.56 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
June 3, 2017

Anti-telomerase cancer therapy: MiR-30 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 3/June/2017, 11.48 pm

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL […]