June

June 2, 2017

Molecular therapy for TIIDM and obesity-associated metabolic deficits: Kallistatin increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 3/June/2017, 12.15 am

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]
June 2, 2017

Natural product-derived Lifespan extension therapy: Isoliquiritigenin(ILQ), isolated from Licorice, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 3/June/2017, 12.03 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
June 2, 2017

Narrow-band Ultraviolet B-based Anti-ageing and Life extension therapy: Narrow-band Ultraviolet B increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 2/June/2017, 11.51 pm

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
June 2, 2017

Narrow band ultraviolet B-based therapy for Inflammatory bowel disease: Narrow band ultraviolet B promotes NFKB-p50/p65 dimer formation, induces inflammatory gene expression downstream of RelA/p65, inhibits colonic pathogenesis, and stalls the progression of inflammatory bowel disease and colitis via down regulation of its target gene, 2/June/2017, 11.45 pm

Introduction: What they say: A study from the Institute for Molecular Medicine, University Medical Center of the Johannes Gutenberg, University of Mainz, Obere Zahlbarer Str, Mainz, […]