July

July 8, 2017

Natural product-derived therapy for prostate cancer: Shikonin, one of the components of Zicao, inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regualtion of its target gene, 9/July/2017, 12.09 am

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent […]
July 8, 2017

Anti-telomerase cancer therapy: α-Solanine, isolated from Solanum Nigrum, suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 8/July/2017, 11.33 pm

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech, from the BioFrontiers Institute, USA, has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: 43) stating that “The TEL patch of telomere protein TPP1 […]
July 8, 2017

Natural product-derived Life-extension therapy: Solasodine, isolated from Solanum Melongena, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 8/July/2017, 11.20 pm

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 […]
July 7, 2017

Vitamin-based therapy for tuberculosis: A form of Vitamin-A deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 7/July/2017, 11.59 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang Technological University, […]