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August 9, 2017

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Fisetin and Vitamin-D dissolved in Hydrogen-rich water activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 9/August/2017, 11.59 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
August 9, 2017

Natural product-derived therapy for gynecologic cancers: Artemisinin, one of the main components  of herb Artemesia Annna L, inhibits the expression of HDAC6, acetylates tumor suppressor proteins, activates tumor suppressor function, and stifles the progression of ARID1A-mutated ovarian cancers via up-regulation of its target gene, 9/August/2017, 11/54 pm

Introduction: What they say: A study from Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA shows that “ARID1A-mutated ovarian cancers depend on […]
August 9, 2017

 Antiviral therapy for HIV virus: Auranofin, a drug used in the treatment of Rheumatoid arthritis,  increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 9/August/2017, 11.46 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Antiviral therapy for HIV virus: Auranofin, a drug used in the treatment of Rheumatoid arthritis, […]
August 9, 2017

Natural product-derived Lifespan extension therapy: Mangiferin, isolated from Mangoes,  prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 9/August/2017, 11.37 pm

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]