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August 22, 2017

Natural product-derived Lifespan extension therapy: Geniposide(GP), isolated from Gardenia,  prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 23/August/2017, 12.11 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
August 22, 2017

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Mangiferin, Diindolylmethane (3,3′-DIM, DIM) and Vitamin-D dissolved in Hydrogen-rich water activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 22/August/2017, 11.48 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
August 22, 2017

Natural product/vitamin-based Combination therapy for PTEN-deficient cancer: A therapeutic mix encompassing Artemisinin, Cholecalciferol and Metformin decreases the expression of CHD1, increases the expression of a number of tumor suppressor genes, inhibits pro-survival TNF-NF-kB gene network, and suppresses tumorigenesis of PTEN-deficient cancer, 22/August/2017, 10.29 pm

Introduction: What they say: A study from the Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA shows that “Synthetic […]
August 22, 2017

Natural product-derived therapy for prostate cancer: A therapeutic mix encompassing N-Acetylcysteine(NAC), Capsaicin, and Sulforaphane (NCS) inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regualtion of its target gene, 22/July/2017, 10.08 pm

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent AMD1 regulation sustains polyamine […]