August

August 8, 2017

Natural product-derived Life-extension therapy: β-Caryophyllene, isolated from Guava, oregano, cinnamon, clove, and black pepper, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 9/August/2017, 12.51 am

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 […]
August 8, 2017

Natural product-derived therapy for gynecologic cancers: Honokiol, one of the main components of herb Magnolia Grandiflora (MG), inhibits the expression of HDAC6, acetylates tumor suppressor proteins, activates tumor suppressor function, and stifles the progression of ARID1A-mutated ovarian cancers via up-regulation of its target gene, 9/August/2017, 12.50 am

Introduction: What they say: A study from Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA shows that “ARID1A-mutated ovarian cancers depend on […]
August 8, 2017

 Lifespan extension therapy: Avermectin, the parent of anti-parasitic drug Ivermecitin, activates autophagy and extends lifespan via up regulation of ATG5, 9/August/2017, 12.46 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
August 7, 2017

Natural product-derived PD-1 pathway activation for Pain therapy: Pyrroloquinoline quinone (PQQ), isolated from Kiwisfruits, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 8/August/2017, 12.57 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]