August

August 26, 2017

Natural product-derived therapy for gynecologic cancers: A therapeutic mix encompassing  Berberine (BER), Dihydroartemisinin (DHA), and Curcumin (CUR)inhibits the expression of HDAC6, acetylates tumor suppressor proteins, activates tumor suppressor function, and stifles the progression of ARID1A-mutated ovarian cancers via up-regulation of its target gene, 26/August/2017, 11.59 pm

Introduction: What they say: A study from Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA shows that “ARID1A-mutated ovarian cancers depend on […]
August 25, 2017

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing Withaferin A (WA), Diindolylmethane (3,3′-DIM, DIM) and Vitamin-D activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 26/August/2017, 1.37 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
August 25, 2017

Natural product-derived therapy for EVI-1-Overexpressing Acute Myeloid Leukemia: Dihydroartemisinin (DHA), isolated from Artemesia Annua L,  decreases the expression of MECOM/EVI-1 and its down target genes, including CKMT-1, alters Arginine-creatine metabolism, inhibits mitochondrial respiration, depletes ATP levels, and promotes regression of EVI-1-overexpressing AML via up regulation of its target gene, 26/August/2017, 12.56 pm

Introduction: What they say: A study from the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; […]
August 25, 2017

Natural product-derived therapy for tuberculosis: β-Cryptoxanthin, isolated from Paprika, Buah Merah, Papaya,  Satsuma Mandarin and among others, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 25/August/2017, 11.59 pm

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]