December

December 8, 2017

Combinatorial therapy for Deafness: a therapeutic mix encompassing N-Acetyl Serotonin, Cholecalciferol, Ajoene and DIM (NACAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 8/December/2017, 12.33 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Combinatorial therapy for Deafness: a therapeutic mix encompassing N-Acetyl Serotonin, Cholecalciferol, Ajoene and DIM (NACAD)  increases the expression […]
December 8, 2017

Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Epigallocatechin-3-0-gallate, isolated from Green tea,  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 8/December/2017, 12.25pm

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
December 8, 2017

Molecular therapy for Diabetic nephropathy (DN): 14,15-Epoxyeicosatrienoic acid increases Pyruvate kinase M2 (PKM2) expression, decreases toxic glucose metabolites, mitochondrial dysfunction and apoptosis, augments glycolytic flux and PGC-1α levels, improves metabolic abnormalities, albuminuria, glomerular pathology, and renal dysfunction and alleviates diabetic nephropathy via down regulation of its target gene, 8/December/2017, 12.18 pm

Introduction: What they say A study from the Research Division, Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA shows that “Pyruvate kinase M2 activation may protect against the […]
December 7, 2017

Natural product-derived therapy for Stroke: Huperzine A attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 7/December/2017, 8.43 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]